Mayl Sakurai, known as Meiru Sakurai (桜井メイル Sakurai Meiru?) in Japan, and as Maylu Sakurai in English anime and manga, is a close friend and classmate of Lan Hikari, Yai Ayanokoji, and Dex Oyama, and is the operator of Roll.EXE. Throughout the Mega Man Battle Network series, she acts as the love interest of Lan, and it is often hinted that the two have feelings for each other, much to the dismay of Dex, who also has feelings for Mayl. This love interest is paralleled by Roll and Lan's NetNavi, MegaMan.EXE, as well as Dex's NetNavi GutsMan.EXE, who has feelings for Roll. Unlike Mayl and Lan, however, Roll is more open with her feelings.

During the epilogue set 20 years after the events of Mega Man Battle Network 6, the final game in the series, it is revealed that Mayl and Lan got married and are living in Lan's old house with their son Patch.

Mayl's parents are not seen in the series, but in Mega Man Battle Network 5, one can see a Vision Burst set 11 years in the past, where it is revealed that her father is Netopian.